First of all, it's ture that nothing can replace anything; It is very significant that the advantages, efficacy, mechanism and the changes brought by antibiotics to our lives.

Antibiotics in aquaculture:

antibiotics

1. the aminoglycoside: neomycin sulfate powder
2. the tetracycline: Doxycycline hydrochloric acid doxycline powder
3. the amideol alcohols: fluorphenicol powder, Thiamphenicol powder

synthetic antibacterial drugs

1. the sulfonamide drugs: compound sulfadiazine powder, sulfamethoxine sodium powder, compound sulfadiazine powder, compound sulfadioxazole powder 
2. the quinolone drugs: enrofloxacin powder, norfloxacin powder, norfloxacin hydrochloride berberine premix, norfloxacin lactate soluble powder, norfloxacin niacin premix and so on.

What is the compound bacteria based on Clostridium butyricum?

The compound bacteria based on Clostridium butyricum is a functional clostridium butyricum compound microecological preparation specially developed by JBH Biotech for intestinal health problems of aquaculture in high protein diet.

It is mainly composed of Clostridium butyricum, Lactobacillus, bacillus subtilis, bacillus licheniformis, protease, amylase, lipase, cellulase, xylanase, mannase and Clostridium butyricum derivatives of special for high protein aquatic animals intestinal prone to intestinal system dysfunction caused by jejunum, empty stomach, white and drag stools, prevents enteritis, which is a high-end products.

What is the difference between antibiotics and the compound bacteria based on Clostridium butyricum?

1. What is the function of antibiotics?

Treatment, the illness need antibiotic to treat;

2. What does the compound bacteria based on Clostridium butyricum do?  

Precaution, reduce the possibility of disease. 

The compound bacteria based on Clostridium butyricum is through the role of probiotics, regulating the intestinal tract, water balance, reducing the incidence of aquaculture animals, no disease no antibiotics.

Therefore the compound bacteria based on Clostridium butyricum can not replace antibiotics; Preventive products cannot replace therapeutic; It is same as health care products and probiotics cannot replace drugs.

3. Again, the concept of treatment and prevention:  ​​​​​​​

The biggest difference is that there must be a loss in the treatment, to some extent, it is reducing the loss, and your benefit must be affected either way;

However, precaution is not: it is about prioritizing a system of barriers that can effectively increase our benefits;

More and more aquaculture people are making their income better with microecology/probiotics than antibiotic.

The effects of the compound bacteria based on Clostridium butyricum:

1. Regulate the balance of intestinal flora: ​​​​​​​

The compound bacteria based on Clostridium butyricum contains a variety of probiotics on intestinal location feature partition different control, the main effect of bacillus in foregut, lactobacillus act mainly on the midgut, Clostridium butyricum mainly on the hindgut. In the whole intestine of aquatic animal, the advantage of probiotic flora is established to benefit the intestine and let the probiotics in the intestine in each region always be in an advantageous position and promote each other in synergy, build barriers (biological barrier, mechanical barrier, chemical barrier, immune barrier) throughout the intestine.

The products of organic acids and antibacterial active substances can inhibit the reproduction of harmful bacteria in the intestine, directly participate in the enzymatic reaction to provide energy required by aquatic animals in stress, improve the activity of immune cells in specific and non-specific immunity, and directly enhance the body's immunity.

2. Improve the integrity of intestinal structure and repair the damaged intestinal tract: ​​​​​​​

it’s metabolites can increase the content of short-chain fatty acids in the intestinal tract of aquatic animals, increase the integrity and compactness of intestinal mucosa, repair the damaged intestinal tract and increase the intestinal surface area.

3. Improve feed conversion rate:​​​​​​​

Increase the surface area of the intestinal tract, bigger the contact area with the feed at the same time, for the compound bacteria based on Clostridium butyricum resistance in a variety of probiotic bacteria can secrete a large number of enzymes, assisted digestion and absorption of aquatic animals, proteins that are not digested and absorbed can be “secondarily fermented” in the hindgut, on the one hand is decomposed into inorganic salt and water after intestinal absorption, on the other hand is used probiotic bacteria breeding, consolidate the beneficial bacterium group, reduce nitrogen discharge and reduce water pressure.

4. Attractant: ​​​​​​​

1. External: soaking or closed activation when mixing materials can make probiotics "wake up" and enter the exponential growth stage, producing rich metabolites.

The acidic aroma of organic acids promotes food attraction, and enzyme products eliminate some of the anti-nutritional factors.

2. Internal: improve digestion and absorption rate, promote intestinal peristalsis, increase appetite and hunger.​​​​​​​

5. Reduce enteritis, white stools, dragging stools and metabolic diseases: ​​​​​​​​​​​​​​

By improving feed utilization, intestinal structural integrity, intestinal barrier function, etc.,reduce intestinal burden, enhance intestinal function and reduce the incidence of intestinal and metabolic nutritional diseases.