C. butyricum (C. butyricum), also known as butyricum, belongs to the genus Clostridium. It is one of the normal flora that is widely found in soil, human and intestinal tracts of various animals. It is a microecological preparation with various biological functions such as regulating the intestinal microecological balance, promoting growth and development, improving immunity, and anti-oxidation.

Secretion of antibacterial substances

As a probiotic, Clostridium butyricum can maintain or restore the dominant intestinal flora of the host in the body. It can inhibit E. coli, Salmonella, Clostridium perfringens, and pylori by secreting short-chain fatty acids, antibacterial peptides and clostridium butyricum. The growth of Helicobacter and other common intestinal pathogens. The secretion of organic acids in the intestine can lower the pH value of the intestinal lumen, restrict the growth of harmful pathogenic bacteria, adjust the microecological balance, reduce enteric toxins, and reduce the rate of diarrhea.

Biological antagonism

Clostridium butyricum has a high adhesion effect to the intestinal tract. It can compete with pathogenic bacteria for colonization sites by adhering to the intestinal epithelial cells, which can inhibit the adhesion of pathogenic bacteria and reduce the adhesion and colonization of pathogenic bacteria to the intestinal mucosa. Opportunity, to a certain extent, reduce the proliferation of pathogenic bacteria and promote the growth of beneficial bacteria.

Promote the growth of probiotics

Digestive enzymes produced by Clostridium butyricum convert polysaccharides into oligosaccharides that are beneficial to the use of probiotics, provide essential growth materials for beneficial intestinal microorganisms, facilitate the growth and reproduction of probiotics, and improve intestinal health.

Protect the intestinal mucosal barrier

Butyric acid can promote colonic protein synthesis, promote cell proliferation, regenerate and repair intestinal epithelial cells, and reverse the increase in intestinal mucosal permeability. Butyric acid is the main nutrient for intestinal epithelial tissue cell regeneration. It can increase the number of intestinal epithelial cells, increase the height of villi, and make the crypts shallow, indicating that it improves the morphology and structure of the intestine, enhances the ability of nutrient absorption, and can also reverse the induction of lipopolysaccharide The decrease in the expression of tight junction protein and occludin protein enhances the tight junctions between cells, reduces cell permeability, and enhances the intestinal barrier function.